Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | the enzyme is dependent on Ca2+ and calmodulin | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Carbachol | increases Ca2+ concentration, MLCK activation and regulatory light chain phosphorylation | Mus musculus | |
KCl | increases Ca2+ concentration, MLCK activation and regulatory light chain phosphorylation | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | the enzyme is dependent on Ca2+ and calmodulin, the intracellular Ca2+ concentration has regulatory effect, overview | Mus musculus | |
Mg2+ | - |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + myosin regulatory light chain | Mus musculus | - |
ADP + phosphorylated myosin regulatory light chain | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bladder | - |
Mus musculus | - |
smooth muscle | from bladder | Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + myosin regulatory light chain | - |
Mus musculus | ADP + phosphorylated myosin regulatory light chain | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MLCK | - |
Mus musculus |
myosin light chain kinase | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |